Clinical Trials in Ireland 2026 — Live Tracker

Low-grade Glioma, Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma, Pediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc. · started 2023-02-27

📍 Crumlin

NCT05566795 on ClinicalTrials.gov ↗

Active Phase 1

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

Amyotrophic Lateral Sclerosis
QurAlis Corporation · started 2022-12-16

📍 Dublin

NCT05633459 on ClinicalTrials.gov ↗

Recruiting Phase 3

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Breast Cancer
Greenwich LifeSciences, Inc. · started 2022-12-16

📍 Dublin

NCT05232916 on ClinicalTrials.gov ↗

Active

APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.

Appetite Loss, Physical Inactivity, Undernutrition, Anorexia of Aging
University College Dublin · started 2022-09-22

📍 Dublin

NCT05608707 on ClinicalTrials.gov ↗

Active Phase 3

A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy

Advanced or Metastatic Non-Small Cell Lung Cancer
AstraZeneca · started 2022-09-15

📍 Cork · Dublin · Limerick

NCT05450692 on ClinicalTrials.gov ↗

Active

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice

Ulcerative Colitis
AbbVie · started 2022-08-15

📍 Abbotstown · Elm Park · Galway

NCT05494606 on ClinicalTrials.gov ↗

Active Phase 3

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

Coronary Artery Disease
Novartis Pharmaceuticals · started 2022-07-08

📍 Dublin · Galway

NCT05360446 on ClinicalTrials.gov ↗

Active Phase 2

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

SSM, Mastocytosis, Indolent, Mastocytosis, Systemic, Mastocytosis
Cogent Biosciences, Inc. · started 2022-06-27

📍 Cork · Dublin

NCT05186753 on ClinicalTrials.gov ↗

Active Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
BeOne Medicines · started 2022-03-10

📍 Dublin · Waterford

NCT05100862 on ClinicalTrials.gov ↗

Active Phase 3

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis
Novartis Pharmaceuticals · started 2021-12-16

📍 Dublin

NCT05147220 on ClinicalTrials.gov ↗

Recruiting

The PIONEER-IV Study is Comparing Clinical Outcomes Between Angiography-derived Physiology Guidance to Usual Care in an All-comers PCI Population With Unrestrictive Use of the HT Supreme Sirolimus-eluting Stent

Coronary Artery Disease
National University of Ireland, Galway, Ireland · started 2021-11-12

📍 Galway

NCT04923191 on ClinicalTrials.gov ↗

Active

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular · started 2021-10-20

📍 Dublin

NCT05198674 on ClinicalTrials.gov ↗

Active Phase 2

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus
Bristol-Myers Squibb · started 2021-10-11

📍 Manorhamilton · Dublin · Galway

NCT04895696 on ClinicalTrials.gov ↗

Active Phase 4

Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism

Pulmonary Embolism
Boston Scientific Corporation · started 2021-08-02

📍 Dublin · Galway

NCT04790370 on ClinicalTrials.gov ↗

Active Phase 3

A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread

Clear Cell Renal Cell Carcinoma
Bristol-Myers Squibb · started 2021-05-21

📍 Tallaght

NCT04810078 on ClinicalTrials.gov ↗

Active Phase 3

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Carcinoma, Renal Cell
Merck Sharp & Dohme LLC · started 2021-04-14

📍 Dublin

NCT04736706 on ClinicalTrials.gov ↗

Recruiting

Medication Following Bariatric Surgery for Type 2 Diabetes Mellitus

Obesity, Type 2 Diabetes
Imperial College London · started 2021-04-01

📍 Dublin

NCT04432025 on ClinicalTrials.gov ↗

Recruiting

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Breast Cancer, Sentinel Lymph Node, Neoplasm, Breast
University Hospitals of Derby and Burton NHS Foundation Trust · started 2021-02-26

📍 Dublin · Galway

NCT04109079 on ClinicalTrials.gov ↗

Active Phase 3

Long-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia A

Hemophilia A
Bioverativ, a Sanofi company · started 2021-02-23

📍 Dublin

NCT04644575 on ClinicalTrials.gov ↗

Recruiting

iCorMicA - Stratified Medicine in Angina

Microvascular Angina, Angina, Stable, Ischemia With No Obstructive Coronary Arteries (INOCA), Coronary Microvascular Dysfunction (CMD)
NHS Greater Glasgow and Clyde · started 2020-12-30

📍 Cork · Dublin

NCT04674449 on ClinicalTrials.gov ↗

Recruiting Phase 1/Phase 2

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

Colorectal Cancer, Pancreatic Cancer, Gastric Cancers, Cholangiocarcinoma
Bold Therapeutics, Inc. · started 2020-08-28

📍 Dublin

NCT04421820 on ClinicalTrials.gov ↗

Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Bayer · started 2020-04-03

📍 Multiple Locations

NCT04142437 on ClinicalTrials.gov ↗

Active

Paediatric Sjögren Syndrome Cohort Study and Repository (PaedSSCoRe)

Sjogren's Syndrome Childhood-onset
University College, London · started 2020-01-11

📍 Dublin

NCT04762108 on ClinicalTrials.gov ↗

Recruiting

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Cutaneous Melanoma, Stage II
Melanoma and Skin Cancer Trials Limited · started 2019-12-17

📍 Cork · Dublin

NCT03860883 on ClinicalTrials.gov ↗

Active Phase 3

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals · started 2019-11-26

📍 Dublin

NCT04153149 on ClinicalTrials.gov ↗

Active

First in Human Clinical Investigation of the FIRE1 System in Heart Failure Patients (FUTURE-HF)

Heart Failure
Foundry Innovation & Research 1, Limited (FIRE1) · started 2019-11-22

📍 Galway

NCT04203576 on ClinicalTrials.gov ↗

Active

Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer

Metastatic Tumors
British Columbia Cancer Agency · started 2019-11-01

📍 Rathgar · Dublin · Cork

NCT03862911 on ClinicalTrials.gov ↗

Active Phase 2/Phase 3

A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis
Janssen Research & Development, LLC · started 2019-09-26

📍 Dublin · Galway

NCT04033445 on ClinicalTrials.gov ↗

Active Phase 3

Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Low Grade Fallopian Tube Serous Adenocarcinoma, Ovarian Low Grade Serous Adenocarcinoma, Primary Peritoneal Low Grade Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v8
NRG Oncology · started 2019-09-20

📍 Cork · Dublin

NCT04095364 on ClinicalTrials.gov ↗

Active

A Multicenter, International, Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® PmVSD Occluder in Patients With Perimembranous Ventricular Septal Defects

Perimembranous Ventricular Septal Defect
Occlutech International AB · started 2019-07-07

📍 Dublin

NCT04034498 on ClinicalTrials.gov ↗

Active Phase 3

A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).

Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Astellas Pharma Global Development, Inc. · started 2018-11-28

📍 Dublin

NCT03653507 on ClinicalTrials.gov ↗

Active Phase 2

Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer
AbbVie · started 2018-10-10

📍 Wilton · Dublin · Elm Park

NCT03539536 on ClinicalTrials.gov ↗

Recruiting

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA)
Novartis Pharmaceuticals · started 2018-09-25

📍 Dublin

NCT04174157 on ClinicalTrials.gov ↗