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Updated 11 Aug 2026 · ClinicalTrials.gov

Clinical Trials in the USA

The most recently updated industry-sponsored clinical trials recruiting across the United States — searchable by condition, sponsor, phase and state. Refreshed daily from the ClinicalTrials.gov registry.

108
Recruiting now
160
Studies tracked
45
States with sites
Recruiting Phase 3
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Plaque Psoriasis
Bristol-Myers Squibb · started 2025-12-03
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Idaho · Indiana
NCT06979453 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Sarcoma,Soft Tissue
Intensity Therapeutics, Inc. · started 2024-06-28
📍 California · Connecticut · Michigan · Nebraska · North Carolina · Ohio · Pennsylvania
NCT06263231 on ClinicalTrials.gov ↗
Recruiting
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
Chronic Pain, Intractable Pain, Low Back Pain, Chronic Low-back Pain
Boston Scientific Corporation · started 2025-11-07
📍 Colorado · Florida · Louisiana · New York · Pennsylvania · South Carolina · Texas
NCT07190807 on ClinicalTrials.gov ↗
Active Phase 2
Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation
Antibody-Mediated Rejection, Kidney Transplantation, Biopsy-proven Histologic Scores, AMR
Alexion Pharmaceuticals, Inc. · started 2025-03-07
📍 Alabama · Arizona · California · Florida · Georgia · Kansas · Michigan · New Jersey
NCT06744647 on ClinicalTrials.gov ↗
Recruiting Phase 3
ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL
CLL / SLL, CLL (Chronic Lymphocytic Leukemia), CLL, Refractory, CLL, Relapsed
Newave Pharmaceutical Inc · started 2026-04-23
📍 Illinois · Maryland · Nevada · Ohio · Pennsylvania · Washington
NCT07342478 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca · started 2025-06-27
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Iowa · Kentucky
NCT07082738 on ClinicalTrials.gov ↗
Recruiting EARLY_Phase 1
Evaluate Advanced Pneumatic Compression Device With Revised Compression Programming for Lymphedema Treatment
Lower Extremity Lymphedema
Tactile Medical · started 2026-07-09
📍 Texas
NCT07613931 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
Huntington Disease
Novartis Pharmaceuticals · started 2026-03-24
📍 California · Colorado · Connecticut · District of Columbia · Florida · Illinois · Indiana · Iowa
NCT07326709 on ClinicalTrials.gov ↗
Starting soon Phase 2
Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease
Grade 2 IDH1-mutant Glioma, Grade 3 IDH1-mutant Glioma, Glioma, IDH1-mutant Glioma
Nuvation Bio Inc. · started 2027-03
📍 California · New Jersey · New York
NCT07703436 on ClinicalTrials.gov ↗
By invitation
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils
Arteriovenous Malformation, Gastrointestinal Bleed, Gastric Varices, Hemorrhoid
Medtronic Endovascular · started 2026-07-24
📍 Texas
NCT07639853 on ClinicalTrials.gov ↗
By invitation Phase 3
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Durvalumab
Cancer
AstraZeneca · started 2022-04-19
📍 California · Colorado · Tennessee
NCT05303532 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
End Stage Kidney Disease
CSL Behring · started 2022-10-21
📍 Alabama · Arizona · California · Colorado · Connecticut · Delaware · Florida · Georgia
NCT05485961 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
Hepatic Impairment
Insmed Incorporated · started 2026-07-14
📍 California · Florida
NCT07643155 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC · started 2026-05-05
📍 Alabama · Arizona · California · Florida · Minnesota · Ohio · South Carolina · Texas
NCT07555483 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia
Schizophrenia
Leal Therapeutics, Inc · started 2026-08
📍 Arkansas · California · Florida · Georgia · Maryland · New Jersey · Texas
NCT07734493 on ClinicalTrials.gov ↗
Recruiting Phase 3
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Endometrial Cancer
AstraZeneca · started 2025-03-27
📍 Arizona · Arkansas · California · Florida · Georgia · Hawaii · Illinois · Louisiana
NCT06989112 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3
Glioma
Boehringer Ingelheim · started 2024-01-30
📍 California · Tennessee
NCT05916313 on ClinicalTrials.gov ↗
Active Phase 2
A Multicenter, Randomized, Double-Masked, Placebo-Controlled Pilot Study to Evaluate the Efficacy and Safety of ZOC2017217 in Subjects With Age-Related Cataract
Age Related Cataracts
Ocusun Ophthalmic Pharmaceutical (Guangzhou) Co., Ltd. · started 2026-02-10
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · North Carolina · North Dakota
NCT07395986 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC
Metastatic Microsatellite-stable Colorectal Cancer
MedImmune LLC · started 2019-09-13
📍 California · Michigan · Nevada · New York · Ohio · Rhode Island · Tennessee · Texas
NCT04068610 on ClinicalTrials.gov ↗
Recruiting
OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
ATTR Amyloidosis
AstraZeneca · started 2023-08-21
📍 Minnesota
NCT06355934 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn About the Safety and Effects of Salanersen (BIIB115) When Given to Babies With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec
Muscular Atrophy, Spinal
Biogen · started 2026-09-04
📍 Texas
NCT07444450 on ClinicalTrials.gov ↗
Recruiting
HeartStart FRx Defibrillator Event Registry
Sudden Cardiac Arrest
Heartstream US LLC · started 2019-11-04
📍 Pennsylvania
NCT04250857 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of TUB-040 Given With Standard Ovarian Cancer Drugs in Patients With Fast-growing Ovarian Cancer
Ovarian Cancer
Tubulis GmbH · started 2026-03-30
📍 California · New Jersey · New York
NCT07736937 on ClinicalTrials.gov ↗
By invitation Phase 3
A Long-term Follow-up Study in Participants Who Received CTX001
Beta-Thalassemia, Thalassemia, Sickle Cell Disease, Hematologic Diseases
Vertex Pharmaceuticals Incorporated · started 2021-01-20
📍 California · Illinois · New York · North Carolina · Pennsylvania · Tennessee · Texas
NCT04208529 on ClinicalTrials.gov ↗
Active
AFFIX: Post-market Study of MaxTack™ Motorized Fixation Device in Subjects Undergoing Ventral Hernia Repair
Ventral Hernia
Medtronic - MITG · started 2025-06-16
📍 Florida · Ohio
NCT06710795 on ClinicalTrials.gov ↗
Recruiting Phase 1
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
Schizophrenia, Schizo-Affective Disorder, Schizophreniform; Schizophrenic, Bipolar Disorder I
BioXcel Therapeutics Inc · started 2021-08-27
📍 California · Florida · Georgia · Texas
NCT05025605 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Alzheimer Disease
Bristol-Myers Squibb · started 2025-07-10
📍 Arizona · California · Colorado · Florida · Louisiana · Maryland · Massachusetts · Michigan
NCT07011732 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate Solrikitug in Participants With COPD (ZION)
COPD
Uniquity One (UNI) · started 2024-08-14
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois
NCT06496620 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate Solriktug in Adult Participants With Asthma
Asthma
Uniquity One (UNI) · started 2024-07-26
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois
NCT06496607 on ClinicalTrials.gov ↗
Recruiting
Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration
Age-Related Macular Degeneration, Age-related Macular Degeneration (ARMD), Intermediate AMD, Geographic Atrophy Secondary to Age-related Macular Degeneration
i-Lumen Scientific AUS PTY LTD · started 2025-05-07
📍 California · Connecticut · Illinois · Nevada · Texas
NCT06662162 on ClinicalTrials.gov ↗
Starting soon
Hypoxic Red Blood Cells in Sickle Cell Anemia
Sickle Cell Anaemia, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children, Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0)
Hemanext · started 2026-09
📍 Connecticut · Georgia · Illinois · Maryland · Pennsylvania
NCT06743113 on ClinicalTrials.gov ↗
Recruiting
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
Parkinson's Disease
Boston Scientific Corporation · started 2014-03-04
📍 California · Colorado · Florida · Idaho · Illinois · Indiana · Massachusetts · Missouri
NCT02071134 on ClinicalTrials.gov ↗
Recruiting
Effect of Sage Extract Supplementation on Cognitive Function in Middle-Aged Men and Women
Cognitive Ability, General
ESM Technologies, LLC · started 2026-02-15
📍 Texas
NCT07757529 on ClinicalTrials.gov ↗
Recruiting
GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections
Aortic Dissection
W.L.Gore & Associates · started 2025-09-22
📍 Alabama · California · Florida · Georgia · Illinois · Indiana · Massachusetts · Michigan
NCT06827990 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors
Solid Tumours
Bristol-Myers Squibb · started 2025-10-15
📍 California · Pennsylvania · South Dakota · Texas · Utah · Washington
NCT07160725 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)
Thyroid Eye Disease, TED, Graves Orbitopathy
Sling Therapeutics, Inc. · started 2026-08-04
📍 Nevada
NCT07753603 on ClinicalTrials.gov ↗
Recruiting Phase 2
Evaluate the Effectiveness and Safety of BBD-1 Multi-target Immune Enhancement Targeting Agent in the Treatment of Hypersensitivity Reaction (IgA) Vasculitis
Allergic Reaction (IgA) Vasculitis
Qifeng Zhang · started 2026-08-10
📍 Maryland
NCT07595367 on ClinicalTrials.gov ↗
Active Phase 1
A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Participants
Epstein-Barr Virus Infection
ModernaTX, Inc. · started 2023-04-05
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Iowa
NCT05831111 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease
Respiratory Syncytial Virus Infections
Shionogi · started 2025-12-11
📍 California · Florida · Georgia · Massachusetts · Missouri · New York · North Carolina · Ohio
NCT07214571 on ClinicalTrials.gov ↗
Recruiting Phase 2
Transition to KPL-387 Monotherapy Dosing & Administration Study
Recurrent Pericarditis, Heart Diseases, Pericarditis
Kiniksa Pharmaceuticals International, plc · started 2026-03-25
📍 Arizona · California · Florida · Illinois · Maryland · Minnesota · New York · Ohio
NCT07288216 on ClinicalTrials.gov ↗
Starting soon
Evaluation of Orthokeratology Lenses With a 5MM Optic Zone Diameter
Myopia, Astigmatism
CooperVision International Limited (CVIL) · started 2026-08
📍 California · Texas
NCT07751172 on ClinicalTrials.gov ↗
Recruiting
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
Malocclusion
Dentsply Sirona Implants and Consumables · started 2026-01-29
📍 California · New Jersey · North Carolina · Texas
NCT07290790 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence
Narcolepsy Type 1, Narcolepsy Type 2
Centessa Pharmaceuticals (UK) Limited · started 2026-05-29
📍 Colorado · Florida · Georgia · Mississippi · North Carolina · Ohio · South Carolina · Texas
NCT07598708 on ClinicalTrials.gov ↗
Active Phase 2
Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Vertex Pharmaceuticals Incorporated · started 2025-11-19
📍 Alabama · California · Connecticut · Florida · Georgia · Illinois · Iowa · Kansas
NCT07161037 on ClinicalTrials.gov ↗
Recruiting Phase 3
Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders
Turner Syndrome, Short Stature Homeobox Gene Mutation, Idiopathic Short Stature, Small for Gestational Age at Delivery
Ascendis Pharma A/S · started 2025-12-12
📍 California · Colorado · Delaware · Florida · Georgia · Idaho · Louisiana · Minnesota
NCT07221851 on ClinicalTrials.gov ↗
Active Phase 3
Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)
Cholestatic Liver Disease (Except ALGS, PFIC, PBC and PSC)
Mirum Pharmaceuticals, Inc. · started 2024-10-14
📍 California · Illinois · New York · Ohio · Texas · Utah
NCT06553768 on ClinicalTrials.gov ↗
Recruiting
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Medtronic MiniMed, Inc. · started 2026-02-02
📍 Arkansas · California · Colorado · Connecticut · Florida · Georgia · Idaho · Illinois
NCT07228117 on ClinicalTrials.gov ↗
Active Phase 3
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer
Breast Neoplasms, Breast Cancer, HER2-positive Early Breast Cancer
AstraZeneca · started 2021-10-25
📍 Arkansas · California · Connecticut · Indiana · Kentucky · Louisiana · Minnesota · Nevada
NCT05113251 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)
Muscular Atrophy, Spinal
Biogen · started 2026-04-28
📍 Illinois · Texas · Virginia
NCT07221669 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Pfizer · started 2024-10-21
📍 Alabama · Arizona · California · Colorado · Florida · Illinois · Kentucky · Maine
NCT06551324 on ClinicalTrials.gov ↗
Recruiting Phase 1
M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors
Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc. · started 2025-10-10
📍 Connecticut · New York · Texas
NCT07166601 on ClinicalTrials.gov ↗
Active Phase 3
A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event
Cardiovascular Disease
AstraZeneca · started 2025-05-28
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Illinois · Indiana
NCT07000123 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
SPEARHEAD-3 Pediatric Study
Synovial Sarcoma, Malignant Peripheral Nerve Sheath Tumor (MPNST), Neuroblastoma (NBL), Osteosarcoma
USWM CT, LLC · started 2023-09-01
📍 California · Maryland · Massachusetts · Missouri · New York · North Carolina · Ohio · Pennsylvania
NCT05642455 on ClinicalTrials.gov ↗
Active Phase 3
Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation
Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer
Mirati Therapeutics Inc. · started 2021-02-23
📍 California · Colorado · Florida · Georgia · Illinois · Indiana · Kansas · Kentucky
NCT04685135 on ClinicalTrials.gov ↗
By invitation
Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
Heart Failure, Heart Failure NYHA Class II, Heart Failure NYHA Class III
CVRx, Inc. · started 2026-04-24
📍 Alabama · Florida · South Dakota · Tennessee · Texas
NCT07232030 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Verastem, Inc. · started 2026-07-22
📍 California · New Jersey · New York · Texas
NCT07659782 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387
Pericarditis, Pericarditis Acute, Recurrent Pericarditis
Kiniksa Pharmaceuticals International, plc · started 2025-07-25
📍 Arizona · California · Colorado · District of Columbia · Georgia · Illinois · Indiana · Kansas
NCT07010159 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Psoriatic Arthritis
Takeda · started 2025-03-03
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Louisiana · Maryland
NCT06671483 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis
Non-cystic Fibrosis Bronchiectasis
UCB Biopharma SRL · started 2026-08-05
📍 Florida · Pennsylvania · Texas
NCT07720375 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
Colorectal Cancer
Verastem, Inc. · started 2026-07-28
📍 California · Florida · Michigan · New Jersey · Texas · Utah · Virginia
NCT07659795 on ClinicalTrials.gov ↗
Recruiting Phase 1
Enzalutamide Implants (Enolen) in Patients With Prostate Cancer
Prostate Adenocarcinoma
Alessa Therapeutics Inc. · started 2024-06-21
📍 California · Illinois · Louisiana · Maryland · Oregon · South Carolina · Virginia · Wisconsin
NCT06257693 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of MGC026 in Participants With Advanced Solid Tumors
Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Squamous Cell Carcinoma of Head and Neck
MacroGenics · started 2024-03-06
📍 California · Michigan · New York · Oregon · Texas · Utah
NCT06242470 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Graves' Disease
Immunovant Sciences GmbH · started 2024-12-17
📍 Arizona · California · Colorado · Delaware · District of Columbia · Florida · Georgia · Indiana
NCT06727604 on ClinicalTrials.gov ↗
By invitation
Interference and Stability Evaluation of the Intelligent Fingerprinting Drug Screening System
Interference With Routine Analytical Tests, Stability of in Vitro Diagnostic Reagents, Illicit Drug Use
Intelligent Bio Solutions Inc. · started 2026-06-15
📍 New Jersey
NCT07758907 on ClinicalTrials.gov ↗
By invitation Phase 3
A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With Binge Eating Disorder
Binge-Eating Disorder
Axsome Therapeutics, Inc. · started 2025-02-20
📍 California · Connecticut · Florida · Georgia · Kansas · Massachusetts · Missouri · New Jersey
NCT06878976 on ClinicalTrials.gov ↗
By invitation Phase 1
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Neoplasms
USWM CT, LLC · started 2018-04-09
📍 Georgia · Maryland · Michigan · Missouri · New York · North Carolina · Oregon · Pennsylvania
NCT03391778 on ClinicalTrials.gov ↗
Recruiting
Patient Retrospective Outcomes (PRO)
Chronic Pain
Boston Scientific Corporation · started 2012-04-03
📍 Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii · Idaho
NCT01550575 on ClinicalTrials.gov ↗
Recruiting
RevCore for In Stent Thrombosis
In-stent Thrombosis
Inari Medical · started 2024-09-09
📍 Connecticut · District of Columbia · Idaho · Maryland · New York · North Carolina · Ohio · Pennsylvania
NCT06394739 on ClinicalTrials.gov ↗
Active
Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea of Adult
Cryosa, Inc. · started 2023-09-12
📍 Colorado · Florida · Illinois · Louisiana · New York · Pennsylvania · Tennessee · Texas
NCT06008626 on ClinicalTrials.gov ↗
Active
A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis
Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
Smith & Nephew, Inc. · started 2021-12-21
📍 Georgia · Massachusetts · Michigan · New York · North Carolina · Oregon · South Carolina · Tennessee
NCT05197036 on ClinicalTrials.gov ↗
Recruiting Phase 3
Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)
EPP, XLP
Tanabe Pharma America, Inc. · started 2021-08-10
📍 California · Florida · Massachusetts · Michigan · Missouri · New York · North Carolina · Ohio
NCT05005975 on ClinicalTrials.gov ↗
Recruiting Phase 2
Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD
Facioscapulohumeral Muscular Dystrophy, FSHD
Scholar Rock, Inc. · started 2026-07-30
📍 Texas
NCT07435129 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
Obesity, Overweight, Overweight With One Weight Related Comorbidity
Hoffmann-La Roche · started 2025-05-05
📍 Alabama · California · Florida · Georgia · Illinois · New York · North Carolina · Ohio
NCT06965413 on ClinicalTrials.gov ↗
Recruiting
Comparative Self-collection for Cervical Cancer Screening Pivotal Study
HPV, HPV - Anogenital Human Papilloma Virus Infection
Mel Mont Medical · started 2026-07-09
📍 Arizona · California · Florida · Idaho · Montana · North Carolina · Texas · Washington
NCT07758140 on ClinicalTrials.gov ↗
Recruiting Phase 3
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
Glioblastoma, Recurrent Glioblastoma, GBM
CarThera · started 2024-01-29
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana · Maryland
NCT05902169 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old
Graves' Disease
Biogen · started 2026-07-30
📍 Texas
NCT07722546 on ClinicalTrials.gov ↗
Recruiting
Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain
Chronic Low-back Pain, Vertebrogenic Pain Syndrome
Boston Scientific Corporation · started 2025-03-26
📍 Arizona · California · Connecticut · District of Columbia · Florida · Georgia · Idaho · Illinois
NCT06827262 on ClinicalTrials.gov ↗
Recruiting Phase 3
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Amyotrophic Lateral Sclerosis
Prilenia · started 2026-02-01
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas · Maryland
NCT07322003 on ClinicalTrials.gov ↗
Active Phase 3
A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
Breast Cancer
AstraZeneca · started 2021-06-22
📍 Massachusetts · North Carolina
NCT04739761 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer
Breast Cancer
Hoffmann-La Roche · started 2026-04-07
📍 California · Minnesota · South Dakota
NCT07405801 on ClinicalTrials.gov ↗
Recruiting
Data Collection Study Using CS (CardiacSense) BP (Blood Pressure) Watch and Pillow Systems
Blood Pressure Monitoring
CardiacSense Ltd. · started 2026-07-21
📍 Colorado
NCT07749963 on ClinicalTrials.gov ↗
Starting soon
The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults
Tyrosol, Creatine, Endurance Performance, Cognition
Applied Science & Performance Institute · started 2026-08-17
📍 Florida
NCT07756658 on ClinicalTrials.gov ↗
Recruiting Phase 1
Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma
Relapsed or Refractory Multiple Myeloma
Jiangsu Simcere Pharmaceutical Co., Ltd. · started 2024-05-24
📍 Arizona · California · Florida · Massachusetts · Minnesota · New York · North Carolina · Tennessee
NCT06375044 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)
Regeneron Pharmaceuticals · started 2024-10-30
📍 Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia · Illinois
NCT06541704 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
Focal Seizures
Jazz Pharmaceuticals · started 2025-11-26
📍 Arizona · California · Connecticut · Florida · Georgia · Illinois · Maryland · Michigan
NCT07233239 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Advanced Solid Tumors, Genital Neoplasm, Female, Urogenital Neoplasms, Lung Neoplasm
Marengo Therapeutics, Inc. · started 2023-01-04
📍 California · Florida · Kansas · Maryland · Massachusetts · Michigan · Ohio · Tennessee
NCT05592626 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Parkinson Disease
Appello Pharmaceuticals, Inc. · started 2026-02-25
📍 Arkansas · California · Colorado · Florida · Georgia · Indiana · Kansas · Kentucky
NCT07432958 on ClinicalTrials.gov ↗
Recruiting Phase 3
Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research
Optic Neuritis
Oculis · started 2026-05-28
📍 Michigan · Texas
NCT07623668 on ClinicalTrials.gov ↗
Recruiting Phase 2
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF)
Anagram Therapeutics, Inc. · started 2026-04-24
📍 California · Colorado · Florida · Illinois · Iowa · Kansas · Kentucky · Maine
NCT07450547 on ClinicalTrials.gov ↗
Recruiting Phase 3
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Primary Biliary Cholangitis
Gilead Sciences · started 2023-09-07
📍 Alabama · Arizona · California · Florida · Georgia · Illinois · Iowa · Kentucky
NCT06051617 on ClinicalTrials.gov ↗
Active
CONtiNuous glucosE Monitoring (CGM) in People wiTh Type 2 Diabetes Not on Insulin
Type 2 Diabetes
DexCom, Inc. · started 2024-08-15
📍 Colorado · Florida · Georgia · Indiana · Minnesota · Missouri · New York · North Carolina
NCT06601166 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Barzolvolimab in Patients With Atopic Dermatitis
Atopic Dermatitis
Celldex Therapeutics · started 2024-12-18
📍 Alabama · California · Florida · Georgia · Idaho · Illinois · Kentucky · Michigan
NCT06727552 on ClinicalTrials.gov ↗
Recruiting
Sonablate HIFU International Registry for PC & BPH Patients
Localized Prostate Cancer, BPH (Benign Prostatic Hyperplasia), Prostate Cancer; Benign Prostatic Hyperplasia
Sonablate · started 2015-01-01
📍 Indiana
NCT07757490 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy
Relapsed or Refractory Large B-cell Lymphoma
Kite, A Gilead Company · started 2026-05-22
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Missouri · Tennessee
NCT07479797 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease
Sjögren, Sjogren Disease, Sjogren's Syndrome
Cullinan Therapeutics Inc. · started 2025-10-01
📍 Florida · New York · Tennessee · Texas · Utah
NCT07041099 on ClinicalTrials.gov ↗
Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Aortic Stenosis, Severe
Edwards Lifesciences · started 2022-06-20
📍 California · Colorado · Connecticut · Florida · Georgia · Illinois · Indiana · Kansas
NCT05172960 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
Neuromyelitis Optica Spectrum Disorder, NMOSD
Hoffmann-La Roche · started 2026-05-06
📍 Colorado
NCT05199688 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping
Duchenne Muscular Dystrophy (DMD)
Dyne Therapeutics · started 2022-08-12
📍 California · Colorado · Georgia · Massachusetts · Ohio · Oregon · Pennsylvania · Utah
NCT05524883 on ClinicalTrials.gov ↗
Active Phase 3
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease
Crohn's Disease
Eli Lilly and Company · started 2020-06-22
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Idaho · Indiana
NCT04232553 on ClinicalTrials.gov ↗
Recruiting Phase 1
A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)
Renal Cell Carcinoma
Bristol-Myers Squibb · started 2026-01-15
📍 Massachusetts · New York · Pennsylvania · Tennessee · Texas
NCT07195682 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
Solid Tumours
AstraZeneca · started 2026-03-17
📍 New York · Rhode Island · Texas · Virginia
NCT07446855 on ClinicalTrials.gov ↗
Recruiting
HeartStart HS1 Defibrillator* Event Registry
Sudden Cardiac Arrest
Heartstream US LLC · started 2021-02-25
📍 Pennsylvania
NCT04840797 on ClinicalTrials.gov ↗
Active Phase 3
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Type 2 Diabetes Mellitus, Chronic Kidney Diseases
Prokidney · started 2022-01-05
📍 Alabama · Arizona · California · Delaware · Florida · Georgia · Idaho · Illinois
NCT05099770 on ClinicalTrials.gov ↗
Active Phase 1
Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Arcellx, Inc. · started 2022-11-28
📍 California · Maryland · Massachusetts · New York · Texas
NCT05457010 on ClinicalTrials.gov ↗
Recruiting
Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System
Venous Embolism of Lower Extremities (Diagnosis), Arterial Embolism and Thrombosis, Acute DVT of Lower Extremity, Chronic DVT of Lower Extremity
Medtronic Endovascular · started 2026-02-24
📍 District of Columbia · Florida · New York · Texas
NCT07335341 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)
Niemann-Pick Type C Disease
Azafaros B.V. · started 2025-06-30
📍 California · Minnesota · Texas · Virginia
NCT07082725 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Phase 1b/2 Study of IV Sarilumab in Adult With RA
Rheumatoid Arthritis
Sanofi · started 2026-07-02
📍 Florida · Pennsylvania · Texas
NCT07704580 on ClinicalTrials.gov ↗
Starting soon
A Registry Study to Assess SYNTHECELTM Dura Repair
Craniotomy
DePuy Synthes Products, Inc. · started 2026-07-31
📍 Florida · Kentucky · Ohio · Texas
NCT07758790 on ClinicalTrials.gov ↗
Recruiting Phase 3
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences · started 2025-03-31
📍 Alabama · Arkansas · California · Florida · Georgia · Massachusetts · Missouri · New York
NCT06911112 on ClinicalTrials.gov ↗
Recruiting
RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Pain
Boston Scientific Corporation · started 2012-11-19
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana · Kansas
NCT01719055 on ClinicalTrials.gov ↗
Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
Diabetes Mellitus, Type I
GentiBio, Inc · started 2025-06-06
📍 California · Florida · Massachusetts · New York · North Carolina
NCT06860516 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
First-in-Human Study of ICT01 in Patients With Advanced Cancer
Solid Tumor, Adult, Hematopoietic/Lymphoid Cancer
ImCheck Therapeutics, an Ipsen company · started 2020-03-05
📍 Arizona · California · Connecticut · Florida · New York · Texas · Washington
NCT04243499 on ClinicalTrials.gov ↗
Active Phase 3
Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome
Gorlin Syndrome
Sol-Gel Technologies, Ltd. · started 2024-03-17
📍 Arkansas · California · Connecticut · Florida · Illinois · Maryland · Michigan · Minnesota
NCT06050122 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension
Hypertension
CRISPR Therapeutics AG · started 2026-08-08
📍 Florida
NCT07758634 on ClinicalTrials.gov ↗
Recruiting
IDEAL: Efficacy of Porcine Placental Extracellular Matrix Augmented Plus Standard of Care (SOC) Versus SOC Alone for the Management of Diabetic Foot Ulcers
Wound Heal, Ulcer
ConvaTec Inc. · started 2025-02-12
📍 California · Florida · Indiana · Maryland · Massachusetts · New York · North Carolina · Pennsylvania
NCT06616844 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy
Muscular Atrophy, Spinal
Hoffmann-La Roche · started 2024-08-14
📍 Arkansas · California · Colorado · Florida · Georgia · Michigan · Pennsylvania · Texas
NCT05861999 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines
Psoriatic Arthritis
Takeda · started 2025-03-10
📍 Arizona · California · Florida · Georgia · Illinois · Kentucky · Maryland · Michigan
NCT06671496 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease
Primary Membranous Nephropathy
AstraZeneca · started 2026-03-28
📍 California · Iowa · Maryland · New York · Texas
NCT07571746 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer (NSCLC)
Servier Bio-Innovation LLC · started 2024-08-07
📍 Michigan · Ohio
NCT06162572 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer
Genentech, Inc. · started 2020-11-06
📍 California · Colorado · Connecticut · District of Columbia · Florida · Illinois · Massachusetts · Michigan
NCT04302025 on ClinicalTrials.gov ↗
Recruiting
Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)
Multiple Sclerosis
Biogen · started 2023-10-27
📍 Colorado · North Carolina
NCT05658497 on ClinicalTrials.gov ↗
Recruiting Phase 4
Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma, Solid Tumor Malignancies
Rigel Pharmaceuticals · started 2026-02-23
📍 California · New York
NCT07486713 on ClinicalTrials.gov ↗
Active Phase 3
A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults
Influenza
ModernaTX, Inc. · started 2026-03-23
📍 California · Georgia · Idaho · Maryland · Nebraska · Ohio · Rhode Island · South Carolina
NCT07496450 on ClinicalTrials.gov ↗
Active Phase 2
Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors
Neoplasms
USWM CT, LLC · started 2019-12-31
📍 California · Colorado · Florida · Illinois · Iowa · Massachusetts · Michigan · Minnesota
NCT03967223 on ClinicalTrials.gov ↗
Recruiting
A Clinical Registry to Demonstrate the Safety and Performance of Teleflex Vascular Access Devices
Vascular Access Device
Teleflex · started 2024-12-08
📍 Alabama · California · Massachusetts
NCT06604039 on ClinicalTrials.gov ↗
Recruiting Phase 2
WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic Pulmonary Fibrosis
Mediar Therapeutics · started 2025-05-05
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas
NCT06967805 on ClinicalTrials.gov ↗
Active Phase 3
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
Coronary Artery Disease
MedTrace Pharma A/S · started 2022-05-08
📍 Iowa · Minnesota · Missouri · Pennsylvania · Texas · Virginia
NCT05134012 on ClinicalTrials.gov ↗
Recruiting Phase 3
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences · started 2025-05-30
📍 California · Colorado · Connecticut · Florida · Maryland · New York · North Carolina · Pennsylvania
NCT06963021 on ClinicalTrials.gov ↗
Recruiting
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
Resistant Hypertension
DeepQure Inc. · started 2024-11-21
📍 California · Florida · Georgia · Michigan · Minnesota
NCT06526858 on ClinicalTrials.gov ↗
Starting soon Phase 2/Phase 3
Global, Multicenter Study of AMT-116 Versus Investigator's Choice in Participants With Advanced or Metastatic Non-squamous EGFR-Wildtype Non-Small Cell Lung Cancer (NSCLC) With Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy
NSCLC (Advanced Non-small Cell Lung Cancer)
Multitude Therapeutics Inc. · started 2026-08-28
📍 Florida · Texas
NCT07718737 on ClinicalTrials.gov ↗
Recruiting Phase 3
ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
X-linked Retinoschisis
Atsena Therapeutics Inc. · started 2023-08-22
📍 Arizona · California · Florida · Massachusetts · Michigan · Minnesota · New York · North Carolina
NCT05878860 on ClinicalTrials.gov ↗
Active
An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment
Von Willebrand Disease, Type 3
Hoffmann-La Roche · started 2025-04-29
📍 California · Minnesota · Missouri
NCT06883240 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Thyroid Eye Disease
Amgen · started 2024-05-30
📍 Arkansas · California · Florida · Illinois · Massachusetts · Nevada · Pennsylvania · Texas
NCT06401044 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.
Chronic Lymphocytic Leukemia, CLL, Mantle Cell Lymphoma, MCL
BeOne Medicines · started 2025-01-23
📍 Florida · Indiana · Kansas · Massachusetts · Missouri · Washington
NCT06697184 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
Pulmonary Arterial Hypertension (PAH), Pulmonary Hypertension, Interstitial Lung Disease
AllRock Bio, Inc. · started 2025-10-01
📍 Arizona · California · Colorado · District of Columbia · Florida · Kansas · Michigan · Ohio
NCT07175038 on ClinicalTrials.gov ↗
Recruiting
Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)
Mitral Regurgitation, Heart Disease
InnovHeart · started 2026-08-05
📍 California · New York · Oregon
NCT07130994 on ClinicalTrials.gov ↗
Recruiting Phase 1
SW-682 in Advanced Solid Tumors
Advanced Solid Tumor, Mesothelioma, Malignant
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany · started 2024-07-31
📍 Arizona · California · Ohio · Oregon · Texas
NCT06251310 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor
PMV Pharmaceuticals, Inc · started 2020-10-29
📍 California · Colorado · Connecticut · Delaware · Florida · Massachusetts · Michigan · Nebraska
NCT04585750 on ClinicalTrials.gov ↗
Starting soon Phase 1
A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar Lines
Glabellar Lines
AbbVie · started 2026-08-10
📍 Illinois
NCT07756580 on ClinicalTrials.gov ↗
Active
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular · started 2021-10-20
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · District of Columbia · Florida
NCT05198674 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Coronavirus Disease (COVID-19)
Merck Sharp & Dohme LLC · started 2024-12-02
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois
NCT06667700 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
Generalized Anxiety Disorder
Definium Therapeutics US, Inc. · started 2025-01-29
📍 Arkansas · California · Florida · Georgia · Maryland · Massachusetts · New Jersey · Ohio
NCT06809595 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Visugromab in Cachexia International Trial
Cancer-associated Cachexia
CatalYm GmbH · started 2026-04-16
📍 Connecticut · Florida · Georgia · New Jersey · Ohio
NCT07112196 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)
Major Depressive Disorder
Definium Therapeutics US, Inc. · started 2025-04-14
📍 Arkansas · California · Colorado · Florida · Illinois · Maryland · Massachusetts · Missouri
NCT06941844 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)
Primary Membranous Nephropathy
Biogen · started 2025-05-22
📍 Alabama · California · Michigan · New York · North Carolina · Ohio · Tennessee · Texas
NCT06962800 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate Safety and Efficacy of ALKS 7290 Compared With Placebo in Adult Participants With Attention Deficit Hyperactivity Disorder (ALKS 7290-201)
Attention Deficit Disorder With Hyperactivity (ADHD)
Alkermes, Inc. · started 2026-08
📍 California · Florida
NCT07755410 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work
Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic
Sanofi · started 2024-07-12
📍 Alabama · California · Colorado · Connecticut · Florida · Illinois · Kansas · Louisiana
NCT06290128 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis
Atopic Dermatitis
Hoffmann-La Roche · started 2025-04-01
📍 California · Florida · Georgia · Indiana · Michigan · Minnesota · New Jersey · New York
NCT06863961 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)
Lipoprotein(a)
Merck Sharp & Dohme LLC · started 2026-06-30
📍 Alabama · California · Connecticut · Florida · Maryland · Michigan · Montana · New Mexico
NCT07614984 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
Gastric Cancer, Gastroesophageal Junction Cancer
Daiichi Sankyo · started 2025-02-27
📍 Connecticut · Illinois · Kansas · Maryland · Massachusetts · Michigan · Minnesota · New York
NCT06731478 on ClinicalTrials.gov ↗
Recruiting Phase 2
KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)
GIST - Gastrointestinal Stromal Tumor, GIST, GIST Metastatic Cancer, Gastro Intestinal Stromal Tumour
Kumquat Biosciences Inc. · started 2026-06-23
📍 California · Florida · Illinois · Iowa · Massachusetts · Michigan · Minnesota · New York
NCT07406633 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Adenovirus Infections
SymBio Pharmaceuticals · started 2026-03-17
📍 Arizona · California · Colorado · District of Columbia · Florida · Georgia · Illinois · Indiana
NCT07387367 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors
Locally Advanced or Metastatic Solid Tumors
Pyrotech Therapeutics, Inc. · started 2024-01-26
📍 California · Florida · Texas
NCT06244992 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)
Homocystinuria
Travere Therapeutics, Inc. · started 2019-01-22
📍 Colorado · Florida · Illinois · Indiana · Maine · Massachusetts · New York · North Carolina
NCT03406611 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)
Low Risk Myelodysplastic Syndromes
Rigel Pharmaceuticals · started 2022-09-12
📍 California · Florida · Missouri · New Jersey · New York · North Carolina · Ohio · Texas
NCT05308264 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC · started 2024-10-21
📍 Arizona · California · Colorado · Connecticut · Florida · Idaho · Illinois · Indiana
NCT06623422 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease
Fabry Disease
Chiesi Farmaceutici S.p.A. · started 2025-07-29
📍 Arizona · Georgia · Iowa · Ohio · Utah · Virginia
NCT06328608 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)
Dry Eye Syndrome, Systemic Lupus Erythematosus
AbbVie · started 2025-08-26
📍 Florida · Illinois · Tennessee · Texas
NCT06977724 on ClinicalTrials.gov ↗
Active Phase 1
The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency
Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency, Autosomal Recessive Hypophosphatemic Rickets, Generalized Arterial Calcification of Infancy, ATP-Binding Cassette Subfamily C Member 6 Deficiency
Inozyme Pharma · started 2023-06-25
📍 California · Ohio · Pennsylvania
NCT05734196 on ClinicalTrials.gov ↗
Active Phase 3
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab
Relapsing Multiple Sclerosis (RMS)
Novartis Pharmaceuticals · started 2025-03-13
📍 Alabama · Arizona · California · Colorado · District of Columbia · Florida · Georgia · Indiana
NCT06869785 on ClinicalTrials.gov ↗
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Priya Life Science (2026). Clinical Trials in the USA Tracker. Available at: https://priyalifescience.com/clinical-trials-usa (Accessed: 12 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one US site, most recently updated first, refreshed daily. This is a curated slice of the full registry, not every US trial. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish and EU sites, see our Ireland and EU trackers.