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Updated 12 Aug 2026 · ClinicalTrials.gov

Clinical Trials in the USA

The most recently updated industry-sponsored clinical trials recruiting across the United States — searchable by condition, sponsor, phase and state. Refreshed daily from the ClinicalTrials.gov registry.

107
Recruiting now
160
Studies tracked
46
States with sites
Recruiting
Study of the Progression of Chronic Cardiovascular Conditions
Cardiovascular Disease (CVD), Heart Failure, Aortic Stenosis, Aortic Stenosis Disease
Prolaio · started 2025-10-30
📍 Illinois
NCT07420907 on ClinicalTrials.gov ↗
Active Phase 3
An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Sanofi · started 2026-03-12
📍 California · Oklahoma
NCT07424144 on ClinicalTrials.gov ↗
Recruiting Phase 2
Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects
Short Bowel Syndrome
Hanmi Pharmaceutical Company Limited · started 2022-03-03
📍 Massachusetts · Ohio
NCT04775706 on ClinicalTrials.gov ↗
Recruiting
Global Paradise System US Post Approval Study
Hypertension, Cardiovascular Diseases, Vascular Diseases
ReCor Medical, Inc. · started 2024-06-28
📍 California · Colorado · Connecticut · Florida · Georgia · Illinois · Kansas · Louisiana
NCT06297291 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
Muscle-invasive Bladder Cancer
Astellas Pharma Global Development, Inc. · started 2026-03-12
📍 Arkansas · Illinois · Michigan · New Jersey · New York · Pennsylvania · South Carolina · Texas
NCT07475806 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Assess the Relative Bioavailability of BMS-986435 and Food Effect on the BMS-986435 in Healthy Adult Participants
Healthy Volunteers
Bristol-Myers Squibb · started 2025-11-12
📍 Florida
NCT07226817 on ClinicalTrials.gov ↗
Recruiting Phase 2
Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody
Clostridioides Difficile Infection
AstraZeneca · started 2025-12-10
📍 Arizona · California · Connecticut · Florida · Georgia · Idaho · Illinois · Kentucky
NCT07285213 on ClinicalTrials.gov ↗
Active
CHAMPION-AF Clinical Trial
Atrial Fibrillation, Stroke, Bleeding
Boston Scientific Corporation · started 2020-10-15
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Delaware · District of Columbia
NCT04394546 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Advanced Solid Malignancies
AstraZeneca · started 2022-06-24
📍 California · Illinois · Massachusetts · New York · Oregon · Texas · Virginia
NCT05417594 on ClinicalTrials.gov ↗
Recruiting Phase 1
Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors
Advanced or Metastatic Solid Tumors
Hanmi Pharmaceutical Company Limited · started 2023-12-28
📍 Florida · Michigan · Ohio · Texas
NCT06234397 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis
Atopic Dermatitis
Organon and Co · started 2025-12-29
📍 Alabama · Arkansas · California · Colorado · Florida · Georgia · Idaho · Illinois
NCT07265479 on ClinicalTrials.gov ↗
Recruiting
PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB
Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Overactive Bladder (OAB)
Axonics, Inc. · started 2025-09-18
📍 Illinois · Missouri
NCT06789406 on ClinicalTrials.gov ↗
Starting soon Phase 4
A Study of Inhaled Treprostinil (LIQ861) in Adults With Pulmonary Arterial Hypertension Transitioning From Oral Selexipag
Pulmonary Arterial Hypertension (PAH)
Liquidia Technologies, Inc. · started 2026-09
📍 Georgia
NCT07759804 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)
Acute Myeloid Leukemia
Debiopharm International SA · started 2025-05-30
📍 California · Florida · Illinois · Michigan · New York · Ohio · Texas
NCT06969430 on ClinicalTrials.gov ↗
Active Phase 3
Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer
Platinum-resistant Ovarian Cancer
Genmab · started 2025-02-07
📍 Alaska · Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii
NCT06619236 on ClinicalTrials.gov ↗
Recruiting Phase 2
HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMB
Von Willebrand Disease (VWD), Heavy Menstrual Bleeding (HMB)
Alnylam Pharmaceuticals · started 2026-07-30
📍 California · Florida · Kentucky
NCT07575308 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Alnylam Pharmaceuticals · started 2026-08-31
📍 Florida
NCT07636811 on ClinicalTrials.gov ↗
Recruiting
Efficacy and Safety of Acute Topical and Aromatic Essential Oil-Based Products for Cognitive Support
Healthy
dōTERRA International · started 2026-06-10
📍 Utah
NCT07623811 on ClinicalTrials.gov ↗
By invitation
IT Matters: The Erectile Restoration Registry
Erectile Dysfunction
Boston Scientific Corporation · started 2021-08-05
📍 California · Florida · Illinois · Indiana · Louisiana · Missouri · North Carolina · Ohio
NCT04200937 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Ulcerative Colitis
Takeda · started 2024-06-12
📍 Alabama · Arizona · California · Florida · Georgia · Illinois · Kansas · Kentucky
NCT06095128 on ClinicalTrials.gov ↗
Recruiting Phase 3
An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency
Ornithine Transcarbamylase Deficiency, Ornithine Transcarbamylase Deficiency Disease, Ornithine Carbamoyltransferase Deficiency (Disorder), Urea Cycle Disorders, Inborn
iECURE, Inc. · started 2024-04-08
📍 California · Colorado · Georgia · Illinois · New York · Oregon
NCT06255782 on ClinicalTrials.gov ↗
Active Phase 4
Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis
Multiple Sclerosis
Novartis Pharmaceuticals · started 2024-11-25
📍 California · Colorado · Illinois · Massachusetts
NCT06444113 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
SMP-3124LP in Adults With Advanced Solid Tumors
Solid Tumor
Sumitomo Pharma America, Inc. · started 2024-08-14
📍 California · Colorado · Florida · Illinois · Ohio · Tennessee · Texas · Washington
NCT06526819 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of PHST001 in Advanced Solid Tumors
Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer, Cholangiocarcinoma
Pheast Therapeutics · started 2025-03-31
📍 California · Colorado · Connecticut · Illinois · Massachusetts · Michigan · New York · North Carolina
NCT06840886 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV
HIV -1 Infection
BioNTech SE · started 2026-02-09
📍 Illinois · Maryland · Missouri · New York
NCT07392372 on ClinicalTrials.gov ↗
Active Phase 2
ADP-A2M4CD8 Monotherapy and in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Ovarian Cancer (SURPASS-3)
Ovarian Cancer
USWM CT, LLC · started 2023-06-26
📍 Arizona · California · Georgia · Michigan · New Jersey · Ohio · Oklahoma · South Dakota
NCT05601752 on ClinicalTrials.gov ↗
Active Phase 2
Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases
Brain Metastases From Solid Tumors
Radiopharm Theranostics, Ltd · started 2024-12-13
📍 Illinois · Indiana · Michigan
NCT06777433 on ClinicalTrials.gov ↗
By invitation
Long-Term Clinical Outcomes Of Subjects Enrolled In The RxSight Light Adjustable Lens (LAL) And Light Delivery Device (LDD) New Enrollment Study
Aphakia Cataract
RxSight, Inc. · started 2025-11-13
📍 Texas
NCT07347379 on ClinicalTrials.gov ↗
Active EARLY_Phase 1
Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects
Electrode Site Reaction
RetMap, Inc · started 2023-03-01
📍 Illinois
NCT05509608 on ClinicalTrials.gov ↗
Active Phase 1
A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma
Advanced Urothelial Carcinoma, Oral Drug Administration, Open Label
Flare Therapeutics Inc. · started 2023-08-24
📍 California · Connecticut · Florida · Illinois · Massachusetts · New York · North Carolina · Ohio
NCT05929235 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder, Depression Disorders
Cybin IRL Limited · started 2025-12-10
📍 Alabama · Arizona · Arkansas · California · Connecticut · Florida · Georgia · Illinois
NCT06793397 on ClinicalTrials.gov ↗
Active Phase 3
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
Major Depressive Disorder
Cybin IRL Limited · started 2024-12-17
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Louisiana · Maryland
NCT06564818 on ClinicalTrials.gov ↗
Recruiting
Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.
Frequency and Type of Medical Adhesive-Related Skin Injury, NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate), Clinician Acceptability of New NPWT Drape, Patient Drop-out Rate From Prescribed NPWT Treatment
Global Biomedical Technologies, LLC · started 2025-02-10
📍 California · Florida · New York
NCT06717308 on ClinicalTrials.gov ↗
Recruiting
A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition
X-Linked Myotubular Myopathy
Astellas Gene Therapies · started 2025-05-19
📍 California · Illinois · Massachusetts · Ohio · Pennsylvania · Utah
NCT06581146 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)
Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation
Bayer · started 2021-10-25
📍 Arizona · California · Georgia · Maryland · Massachusetts · Michigan · New York · Tennessee
NCT05099172 on ClinicalTrials.gov ↗
Recruiting
Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations
Clonal Mast Cell Disease, KIT D816V Mutation, Suspected KITD816V Mutated Clonal Mast Cell Disease
Blueprint Medicines Corporation · started 2025-10-17
📍 Alabama · California · Florida · Georgia · Illinois · Kansas · Louisiana · Maryland
NCT07143669 on ClinicalTrials.gov ↗
Starting soon Phase 2
A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Disease, Chronic Obstructive
Eli Lilly and Company · started 2026-08
📍 Alabama · California · Colorado · Florida · Illinois · Indiana · Massachusetts · Michigan
NCT07759245 on ClinicalTrials.gov ↗
Active
NEUROMARK Registry Study
Chronic Rhinitis
Neurent Medical · started 2023-06-12
📍 Alabama · California · Florida · Kentucky · Texas · Utah · Virginia
NCT05937308 on ClinicalTrials.gov ↗
Active
Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC
Non-infected Venous Leg Ulcer, Venous Leg Ulcer, Venous Insufficiency, Venous Stasis
BioStem Technologies · started 2025-02-14
📍 Alabama · California · Florida · Illinois · Massachusetts · Missouri · New York · Texas
NCT06811909 on ClinicalTrials.gov ↗
Recruiting Phase 3
Supporting Weak Immune System During Autoimmune Therapy: Testing Panzyga to Prevent Infections
Hypogammaglobulinemia, Autoimmune Conditions, Rheumatic Conditions, Infections
Octapharma · started 2026-06-10
📍 Arizona
NCT07220915 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)
Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals · started 2024-11-11
📍 Arkansas · California · Colorado · District of Columbia · Florida · Georgia · Idaho · Illinois
NCT06719141 on ClinicalTrials.gov ↗
Recruiting Phase 2
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Rhinovirus Infection
Altesa Biosciences, Inc. · started 2026-05-01
📍 Alabama · Arizona · California · Florida · Georgia · Illinois · Indiana · Kentucky
NCT07610395 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome
Phelan-McDermid Syndrome
Neuren Pharmaceuticals Limited · started 2025-11-12
📍 Alabama · California · Illinois · Maryland · Massachusetts · Michigan · New York · Ohio
NCT07281079 on ClinicalTrials.gov ↗
Recruiting Phase 1
FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer
Breast Cancer
Regor Pharmaceuticals Inc. · started 2022-03-04
📍 California · Florida · Georgia · Massachusetts · Missouri · New York
NCT05304962 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Atopic Dermatitis, Atopic Dermatitis Eczema, Eczema
Inmagene LLC · started 2025-06-17
📍 California · Florida · Illinois · New York · North Carolina · North Dakota · Ohio · Oregon
NCT07037901 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder
Generalized Anxiety Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. · started 2026-07-28
📍 Florida · New York · Texas
NCT07759128 on ClinicalTrials.gov ↗
Recruiting
Cognition and Imaging With Tigertriever
Stroke
Rapid Medical · started 2024-10-28
📍 California · Michigan · New York
NCT05531461 on ClinicalTrials.gov ↗
Recruiting
Pro-2-Cool Pivotal Trial II
Concussion, Mild
TecTraum Inc. · started 2025-02-20
📍 Michigan · Ohio
NCT06929923 on ClinicalTrials.gov ↗
Active
A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care
Eosinophilic Esophagitis (EoE)
Regeneron Pharmaceuticals · started 2024-11-22
📍 Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia · Illinois
NCT06693531 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Metastatic Breast Cancer
Hoffmann-La Roche · started 2018-03-30
📍 California · Colorado · Florida · Minnesota · Nevada · New Jersey · New York · North Carolina
NCT03424005 on ClinicalTrials.gov ↗
Active Phase 3
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis Naive to Biologic Disease-Modifying Antirheumatic Drug
Arthritis, Psoriatic
MoonLake Immunotherapeutics AG · started 2024-10-15
📍 Arizona · California · Florida · Illinois · Louisiana · Maryland · Michigan · North Carolina
NCT06641076 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Non-Small Cell Lung Cancer
AstraZeneca · started 2024-04-11
📍 Alaska · Arizona · Arkansas · California · Florida · Georgia · Illinois · Indiana
NCT06357533 on ClinicalTrials.gov ↗
Recruiting
Axonics R20 Post-Market Clinical Follow-up (PMCF) Study for the Indication of Fecal Incontinence
Fecal Incontinence
Axonics, Inc. · started 2026-07-02
📍 New York · Texas
NCT07499258 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)
Hereditary Hemorrhagic Telangiectasia
Alnylam Pharmaceuticals · started 2024-11-07
📍 Alabama · California · Florida · Indiana · Massachusetts · Minnesota · Missouri · North Carolina
NCT06659640 on ClinicalTrials.gov ↗
By invitation Phase 2/Phase 3
HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP
Erythropoietic Protoporphyria
Disc Medicine, Inc · started 2023-08-31
📍 Alabama · California · Florida · Massachusetts · New York · North Carolina · Ohio · Pennsylvania
NCT05883748 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
Acute Migraine
Kallyope Inc. · started 2026-08-03
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Georgia · Illinois
NCT07674654 on ClinicalTrials.gov ↗
Active Phase 1
A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms
Myeloproliferative Neoplasms
Incyte Corporation · started 2024-08-08
📍 Alabama · California · Florida · Illinois · Kansas · Michigan · New York · Oregon
NCT06313593 on ClinicalTrials.gov ↗
Recruiting
A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Suicide, Mental Health Disorder, Anhedonia
Ksana Health · started 2026-06-18
📍 Oregon · Pennsylvania
NCT07348666 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
Early-Onset Alzheimer Disease
Alnylam Pharmaceuticals · started 2022-02-04
📍 California · Indiana
NCT05231785 on ClinicalTrials.gov ↗
By invitation Phase 3
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)
Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals · started 2025-02-12
📍 Arkansas · California · Colorado · Florida · Idaho · Maryland · Massachusetts · Minnesota
NCT06908226 on ClinicalTrials.gov ↗
Recruiting Phase 2
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
Regeneron Pharmaceuticals · started 2025-05-28
📍 Alabama · California · Florida · Illinois · Kansas · Kentucky · Massachusetts · Michigan
NCT06787612 on ClinicalTrials.gov ↗
Recruiting Phase 2
Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity
Primary Sjögren's Syndrome
Immunovant Sciences GmbH · started 2025-06-30
📍 California · Colorado · Florida · Illinois · Louisiana · New York · Pennsylvania · Tennessee
NCT06979531 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors
Advanced Solid Tumor, Metastatic Solid Tumor
Daiichi Sankyo · started 2023-08-18
📍 Florida · Kansas · Oregon · Rhode Island · Texas · Utah · Wisconsin
NCT05875168 on ClinicalTrials.gov ↗
Starting soon
Comparison of Four Qualia Sleep Formulations on Sleep Quality : An Open-label 4-arm Pilot Study
Sleep Quality
Qualia Life Sciences · started 2026-08-28
📍 California
NCT07744971 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort
Chronic Kidney Disease
AstraZeneca · started 2025-06-09
📍 California · Illinois · Michigan · Minnesota · Texas
NCT07024823 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer, Endometrial Cancer
AstraZeneca · started 2021-10-18
📍 California · Louisiana · Maryland · Massachusetts · Missouri · New Mexico · New York · North Carolina
NCT05123482 on ClinicalTrials.gov ↗
Active
The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates · started 2023-03-02
📍 California · Connecticut · District of Columbia · Florida · Illinois · Massachusetts · Michigan · New Jersey
NCT05489588 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects
Multiple Myeloma (MM)
C4 Therapeutics, Inc. · started 2026-02-06
📍 Arizona · California · Florida · Georgia · Illinois · Indiana · Kentucky · Maryland
NCT07280013 on ClinicalTrials.gov ↗
Recruiting Phase 1
Anti-GD2 ADC M3554 in Advanced Solid Tumors
Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc. · started 2024-11-08
📍 Massachusetts · New York · Texas
NCT06641908 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Learn About How Well BAY 3401016 Works in Adults With Alport Syndrome
Alport Syndrome
Bayer · started 2025-11-19
📍 Alabama · Florida · Georgia · Idaho · Massachusetts · Texas
NCT07211685 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
Atopic Dermatitis, Atopic, Dermatitis, Dermatitis, Atopic
Apollo Therapeutics Ltd · started 2026-05-28
📍 Alabama · Arizona · Arkansas · California · Colorado · Florida · Georgia · Idaho
NCT07599813 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of GEN1106 in Participants With Solid Tumors
Solid Tumors, Urothelial Carcinoma
Genmab · started 2026-04-14
📍 Connecticut · New York · South Carolina · Tennessee · Texas
NCT07416123 on ClinicalTrials.gov ↗
Active
Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer
Prostate Cancer
Boston Scientific Corporation · started 2021-12-21
📍 Florida · Kansas · Michigan · New Jersey · Pennsylvania · South Carolina
NCT04905069 on ClinicalTrials.gov ↗
Active
F15 Recharge Free Axonics SNM System Clinical Study
Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI)
Axonics, Inc. · started 2023-12-08
📍 Connecticut · Florida · Georgia · Minnesota · Nebraska · New York · Oregon · South Carolina
NCT06186765 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)
Primary Hyperoxaluria Type 1, PH1
YolTech Therapeutics Co., Ltd · started 2026-08
📍 Alabama
NCT07587021 on ClinicalTrials.gov ↗
Active Phase 3
Study of Bitopertin in Participants With EPP or XLP (APOLLO)
Erythropoietic Protoporphyria (EPP), X-Linked Protoporphyria (XLP)
Disc Medicine, Inc · started 2025-04-04
📍 California · Florida · Massachusetts · Michigan · New York · North Carolina · Ohio · Texas
NCT06910358 on ClinicalTrials.gov ↗
Recruiting Phase 3
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
Generalized Myasthenia Gravis
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany · started 2024-06-25
📍 Arizona · Colorado · Connecticut · District of Columbia · Florida · Kansas · North Carolina · Ohio
NCT06463587 on ClinicalTrials.gov ↗
Recruiting
Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)
Orthostatic Hypotension, Reflex Syncope
Boston Scientific Corporation · started 2026-08-06
📍 Minnesota
NCT07502599 on ClinicalTrials.gov ↗
Active Phase 2
A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma
Asthma
GlaxoSmithKline · started 2025-02-10
📍 Arkansas · California · Colorado · Connecticut · Florida · Illinois · Louisiana · Michigan
NCT06748053 on ClinicalTrials.gov ↗
Recruiting Phase 2
ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection
Clostridium Difficile Infection Recurrence
Acurx Pharmaceuticals Inc. · started 2026-08-06
📍 California · Connecticut · Florida · Georgia · Idaho · Illinois · Massachusetts · Michigan
NCT07513285 on ClinicalTrials.gov ↗
Starting soon Phase 3
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
AstraZeneca · started 2026-08-28
📍 Alabama · California · Connecticut · Florida · Georgia · Illinois · Indiana · Iowa
NCT07761117 on ClinicalTrials.gov ↗
Recruiting
Pedal Pump Clinical Trial on Edema V1
Lower Extremity Edema, Congestive Heart Failure(CHF), Chronic Venous Insufficiency (CVI), Kidney Disease
David McVay · started 2026-08-06
📍 Oklahoma
NCT07760363 on ClinicalTrials.gov ↗
Recruiting
EVERO Drug-coated Balloon (DCB) Randomized Trial
Peripheral Vascular Disease, Peripheral Arterial Disease
Cook Research Incorporated · started 2026-04-17
📍 Connecticut · Florida · Iowa · Mississippi · South Carolina · Texas
NCT07144150 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Bristol-Myers Squibb · started 2026-03-13
📍 Arizona · California · Florida · Georgia · Illinois · Iowa · Minnesota · Missouri
NCT07221149 on ClinicalTrials.gov ↗
Active
P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation
Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System, Atrial Fibrillation (Paroxysmal), Pulmonary Vein Isolation
CathVision ApS · started 2026-04-13
📍 New Jersey
NCT07471308 on ClinicalTrials.gov ↗
Recruiting Phase 3
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
Arthritis, Psoriatic
MoonLake Immunotherapeutics AG · started 2024-10-15
📍 Arizona · Arkansas · California · Florida · Georgia · Illinois · Louisiana · Maryland
NCT06641089 on ClinicalTrials.gov ↗
Starting soon Phase 1/Phase 2
XVIE to Treat Androgenetic Alopecia (AGA)
Androgenetic Alopecia
Restore Biologics Holdings, Inc. dba Xtressé · started 2026-12-01
📍 Florida · Maryland
NCT07482423 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
Lupus Erythematosus, Systemic
AstraZeneca · started 2025-04-21
📍 California · Florida · Georgia · Illinois · Maryland · Massachusetts · Missouri · New York
NCT06897930 on ClinicalTrials.gov ↗
Active
Paresthesia-Free Fast-Acting Subperception (FAST) Study
Chronic Pain
Boston Scientific Corporation · started 2021-02-10
📍 California · Colorado · Florida · Illinois · Indiana · Louisiana · New York · North Carolina
NCT04618471 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression
Ovarian Cancer
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc · started 2026-04-17
📍 Arizona · California · New Jersey · Ohio · Oregon · Pennsylvania · South Dakota
NCT07546500 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease
Graves' Disease, Graves Disease
argenx · started 2026-06-10
📍 California · Florida · Kansas · Michigan · New York · Texas
NCT07570316 on ClinicalTrials.gov ↗
Recruiting Phase 3
An Open-label Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome
Phelan-McDermid Syndrome
Neuren Pharmaceuticals Limited · started 2026-06-08
📍 California · Maryland · Massachusetts · Ohio · Texas
NCT07593391 on ClinicalTrials.gov ↗
Active Phase 1
Study of CHS-114 in Participants With Advanced Solid Tumors
Advanced Solid Tumor, Head and Neck Squamous Cell Carcinoma
Coherus Oncology, Inc. · started 2022-12-15
📍 California · Georgia · Kentucky · Maryland · Michigan · Missouri · Ohio · Tennessee
NCT05635643 on ClinicalTrials.gov ↗
Recruiting
Aquarius Pilot Study to Evaluate the New Axonics Trial System
Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI), Overactive Bladder (OAB)
Axonics, Inc. · started 2026-04-30
📍 South Carolina
NCT07335484 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Trial to Examine if Repinatrabit is Processed Differently in Adults With Reduced Liver or Kidney Function Compared to Adults With Normal Liver and Kidney Function
Phenylketonuria
Otsuka Pharmaceutical Development & Commercialization, Inc. · started 2026-07-17
📍 Florida
NCT07713758 on ClinicalTrials.gov ↗
Active Phase 3
A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.
Generalized Myasthenia Gravis
Novartis Pharmaceuticals · started 2024-07-31
📍 Arizona · California · Georgia · Illinois · Maryland · Massachusetts · Michigan · North Carolina
NCT06517758 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
Myelofibrosis; Anemia, Anemia, Myelofibrosis, Myelofibrosis Due to and Following Polycythemia Vera
Disc Medicine, Inc · started 2022-06-06
📍 Arizona · California · Colorado · Florida · Georgia · Michigan · Minnesota · Missouri
NCT05320198 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc. · started 2025-12-11
📍 California · Colorado · Georgia · Illinois · Maryland · Michigan · Minnesota · Pennsylvania
NCT07144163 on ClinicalTrials.gov ↗
Recruiting Phase 2
Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)
Invasive Fungal Infection
Merck Sharp & Dohme LLC · started 2022-02-22
📍 California · Florida · Illinois · North Carolina · Texas
NCT04665037 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
Low Grade Serous Ovarian Cancer
Verastem, Inc. · started 2024-03-18
📍 Arizona · Arkansas · California · Connecticut · Florida · Georgia · Illinois · Louisiana
NCT06072781 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals · started 2025-06-17
📍 Illinois · New York · Ohio · Pennsylvania
NCT07037771 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC), G12D Mutated KRAS
Verastem, Inc. · started 2026-06-16
📍 California · Florida · Maryland · Massachusetts · Michigan · Missouri · New Jersey · New York
NCT07644559 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib (LOU064) in Adult Patients With Papulopustular Rosacea (PPR)
Papulopustular Rosacea
Novartis Pharmaceuticals · started 2026-07-30
📍 Texas
NCT07681271 on ClinicalTrials.gov ↗
Active Phase 3
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
Heart Failure
Novo Nordisk A/S · started 2023-05-08
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia
NCT05636176 on ClinicalTrials.gov ↗
Recruiting
Sacral Neuromodulation for Male Overactive Bladder (MOAB)
Overactive Bladder, Urinary Urgency Incontinence, Benign Prostatic Hyperplasia, Prostate Cancer
Axonics, Inc. · started 2024-10-22
📍 Alabama · Arizona · California · Florida · Louisiana · Maryland · Michigan · Minnesota
NCT06511141 on ClinicalTrials.gov ↗
Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Refractory Angina
Shockwave Medical, Inc. · started 2022-01-04
📍 Arizona · California · Colorado · Connecticut · District of Columbia · Florida · Georgia · Illinois
NCT05102019 on ClinicalTrials.gov ↗
Recruiting Phase 3
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome
Angelman Syndrome
Ionis Pharmaceuticals, Inc. · started 2025-06-10
📍 California · Colorado · District of Columbia · Florida · Georgia · Illinois · Massachusetts · Missouri
NCT06914609 on ClinicalTrials.gov ↗
Recruiting Phase 2
Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)
Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)
Stingray Therapeutics · started 2024-11-20
📍 New Jersey · Texas · Washington
NCT06589440 on ClinicalTrials.gov ↗
Active Phase 1
ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)
Endometrial Cancer, Esophageal Cancer, Esophagogastric Junction (EGJ), Gastric (Stomach) Cancer
USWM CT, LLC · started 2019-08-20
📍 Florida · Massachusetts · Missouri · New York · North Carolina · Oklahoma · Tennessee · Texas
NCT04044859 on ClinicalTrials.gov ↗
Recruiting
NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study
Intracranial Aneurysm
Medtronic Neurovascular Clinical Affairs · started 2025-12-12
📍 Florida · Georgia · Indiana · Iowa · Michigan · Missouri · South Carolina · Tennessee
NCT06604884 on ClinicalTrials.gov ↗
Active
SpaceIT Hydrogel System for Perirectal Spacing
Prostate Cancer
Boston Scientific Corporation · started 2024-10-30
📍 California · Florida · Georgia · Illinois · Kansas · New York · Ohio · Pennsylvania
NCT06451614 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
TP53 Y220C Mutation, Advanced Solid Tumors
PMV Pharmaceuticals, Inc · started 2026-02-04
📍 Colorado · Florida · Tennessee · Texas
NCT07372625 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Evaluate RLS-1496 Topical Cream for Actinic Keratosis
Actinic Keratosis (AK)
Rubedo Life Sciences, Inc. · started 2026-02-03
📍 Arkansas · Minnesota · Nebraska · Texas
NCT07340697 on ClinicalTrials.gov ↗
Starting soon
Safety and Efficacy of a 2,910 nm Fractional Ablative Fiber Laser (UltraClear®) for Improvements of Skin Laxity and Lifting of the Lower Face, Submental, and Neck Treatment Areas
Skin Laxity (Submental and Neck), Skin Lifting and Tightening
FA Corporation · started 2026-08-07
📍 Kentucky · Texas
NCT07759817 on ClinicalTrials.gov ↗
Recruiting
Cryoablation for Monomorphic Ventricular Tachycardia (VTS)
Ventricular Tachycardia, Sustained, Ventricular Tachycardia, Monomorphic
Adagio Medical · started 2026-08-01
📍 Arizona · California · Massachusetts · New York · Pennsylvania · South Carolina · Tennessee · Virginia
NCT07650032 on ClinicalTrials.gov ↗
Recruiting
GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study
Aortic Arch Dissection, Aortic Arch Aneurysm
W.L.Gore & Associates · started 2026-03-02
📍 California · Connecticut · District of Columbia · Florida · North Carolina · Pennsylvania · Texas · Utah
NCT07166133 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
EDS, Cataplexy, Fatigue, Narcolepsy
Harmony Biosciences Management, Inc. · started 2026-06-04
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana
NCT07675135 on ClinicalTrials.gov ↗
Active
Stone and Laser Therapies Post-Market Study (SALT)
Benign Prostate Hypertrophy(BPH), Renal Calculi, Ureteral Stones, Kidney Stones, Calculi, Urinary
Boston Scientific Corporation · started 2025-06-30
📍 Arizona · Florida · Indiana · North Carolina
NCT06982235 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
Bronchiectasis
GlaxoSmithKline · started 2025-10-30
📍 Alabama · Arizona · California · Colorado · Florida · Indiana · Louisiana · Maryland
NCT07201051 on ClinicalTrials.gov ↗
Starting soon
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health
Healthy Aging, Inflammaging, Metabolic Health, Quercetin
Applied Science & Performance Institute · started 2026-08
📍 Florida
NCT07760506 on ClinicalTrials.gov ↗
Recruiting
PULSED AF Post-Approval Study
Atrial Fibrillation
Medtronic Cardiac Ablation Solutions · started 2024-11-04
📍 Florida · Georgia · Illinois · Kentucky · Massachusetts · Michigan · Nebraska · New York
NCT06578104 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
Colorectal Cancer
Kahr Bio Australia Pty Ltd · started 2026-01-16
📍 Colorado · Florida · North Carolina · Pennsylvania · Texas
NCT07235293 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc. · started 2026-01-22
📍 California · Massachusetts · Michigan · Minnesota · New Jersey · New York · Pennsylvania · Texas
NCT07159841 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
Major Depressive Disorder (MDD)
Draig Therapeutics Ltd · started 2026-05-14
📍 Arizona · Arkansas · California · Florida · Georgia · Illinois · Massachusetts · New York
NCT07610473 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Alzheimer's Disease
Bristol-Myers Squibb · started 2025-07-21
📍 California · Colorado · Florida · Illinois · Indiana · Massachusetts · Michigan · Mississippi
NCT06976203 on ClinicalTrials.gov ↗
Active
Head and Intraocular Trauma Tool for the Identification of Mild Traumatic Brain Injury
Brain Injuries, Traumatic
Rebiscan, Inc. · started 2021-12-01
📍 Virginia
NCT05092295 on ClinicalTrials.gov ↗
Recruiting Phase 3
Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia
Hypertriglyceridemia
Arrowhead Pharmaceuticals · started 2025-04-09
📍 California · Florida · Georgia · Illinois · Indiana · Kansas · Maryland · Michigan
NCT06822790 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Graves' Disease
Immunovant Sciences GmbH · started 2025-06-19
📍 Arizona · California · Colorado · Florida · Georgia · Kansas · Kentucky · Missouri
NCT07018323 on ClinicalTrials.gov ↗
Starting soon
Comparing Facial Aging Between Identical Twins With 3D Imaging
Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
Ponsky Facial Aesthetics And Plastic Surgery, Llc · started 2026-08-08
📍 Ohio
NCT07760532 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
PIK3CA-Related Overgrowth Spectrum (PROS), Lymphatic Malformations, Vascular Malformations, PIK3CA Mutation
Relay Therapeutics, Inc. · started 2025-06-13
📍 Arizona · Arkansas · California · Colorado · Georgia · Indiana · Iowa · Maryland
NCT06789913 on ClinicalTrials.gov ↗
Recruiting
A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health
Dental Plaque, Gingivitis
HALEON · started 2026-07-13
📍 Indiana
NCT07704905 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Safety of HRX215 in Patients After Minor and Major Liver Resection
Liver Resection, Colorectal Carcinoma Liver Metastases
HepaRegeniX GmbH · started 2025-05-06
📍 Maryland · Minnesota · Ohio
NCT06638502 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-study
Epidermolysis Bullosa (EB), Dystrophic Epidermolysis Bullosa, Junctional Epidermolysis Bullosa
Xinnate AB · started 2026-01-30
📍 Ohio
NCT06594393 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals · started 2026-01-15
📍 California
NCT07465224 on ClinicalTrials.gov ↗
Recruiting Phase 3
Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS
Short Bowel Syndrome
Zealand Pharma · started 2026-02-11
📍 Illinois · Missouri · Nebraska · New York · Tennessee
NCT07197944 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)
Ischemic Stroke
Clarion Cells, Inc. · started 2021-01-04
📍 California
NCT04631406 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease
Crohn's Disease
Takeda · started 2024-04-18
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Illinois · Kansas
NCT06045754 on ClinicalTrials.gov ↗
Active Phase 3
Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.
Eosinophilic Granulomatous Vasculitis
AstraZeneca · started 2019-10-29
📍 Colorado · Michigan · Minnesota · New Mexico · New York · Pennsylvania · Texas · Washington
NCT04157348 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma, Mantle-cell Lymphoma, Large B-cell Lymphoma
AstraZeneca · started 2025-01-30
📍 Massachusetts · New Jersey · New York · North Carolina · Ohio · Oregon · Pennsylvania · Rhode Island
NCT06564038 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Gilead Sciences · started 2025-04-04
📍 Alaska · Arkansas · California · Florida · Illinois · Indiana · Kentucky · Maine
NCT06801834 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies
Neoplasm, Cancer, Malignant Tumors
Compugen Ltd · started 2025-01-07
📍 Connecticut · Massachusetts · Michigan · Tennessee · Texas · Virginia
NCT06759649 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
Focal Seizure, Epilepsy, Focal Epilepsy
Rapport Therapeutics Inc. · started 2026-06-05
📍 California · Florida · Georgia · Idaho · Indiana · Maryland · New Jersey · Pennsylvania
NCT07563881 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma
Refractory Melanoma
Diakonos Oncology Corporation · started 2026-04-06
📍 Alabama · Arizona · California · Massachusetts · New Jersey · North Carolina · Texas
NCT07288112 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and Pediatric Participants With Allergic Conjunctivitis Due to Cat Allergy
Allergic Conjunctivitis
Regeneron Pharmaceuticals · started 2026-07-31
📍 Massachusetts
NCT07675811 on ClinicalTrials.gov ↗
Recruiting
Respiration Measured Via End-tidal CO2 and Spirometry Study (RESPI)
Respiration Rate Detection
Boston Scientific Corporation · started 2026-05-28
📍 Minnesota
NCT07537478 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors
Solid Tumor
PAQ Therapeutics, Inc. · started 2024-12-19
📍 California · Massachusetts · Michigan · Tennessee · Texas · Utah · Virginia
NCT06797336 on ClinicalTrials.gov ↗
Active Phase 2
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
Prostate Cancer
Astellas Pharma Global Development, Inc. · started 2016-12-22
📍 Alaska · Arizona · California · Colorado · District of Columbia · Florida · Illinois · Indiana
NCT02960022 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping
Duchenne Muscular Dystrophy (DMD)
Dyne Therapeutics · started 2022-08-12
📍 California · Colorado · Georgia · Massachusetts · Ohio · Oregon · Pennsylvania · Utah
NCT05524883 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy
Relapsed or Refractory Large B-cell Lymphoma
Kite, A Gilead Company · started 2026-05-22
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Missouri · Tennessee
NCT07479797 on ClinicalTrials.gov ↗
Recruiting Phase 2
Evaluate the Effectiveness and Safety of BBD-1 Multi-target Immune Enhancement Targeting Agent in the Treatment of Hypersensitivity Reaction (IgA) Vasculitis
Allergic Reaction (IgA) Vasculitis
Qifeng Zhang · started 2026-08-10
📍 Maryland
NCT07595367 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer (NSCLC)
Servier Bio-Innovation LLC · started 2024-08-07
📍 Michigan · Ohio
NCT06162572 on ClinicalTrials.gov ↗
Active
CONtiNuous glucosE Monitoring (CGM) in People wiTh Type 2 Diabetes Not on Insulin
Type 2 Diabetes
DexCom, Inc. · started 2024-08-15
📍 Colorado · Florida · Georgia · Indiana · Minnesota · Missouri · New York · North Carolina
NCT06601166 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Verastem, Inc. · started 2026-07-22
📍 California · New Jersey · New York · Texas
NCT07659782 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old
Graves' Disease
Biogen · started 2026-07-30
📍 Texas
NCT07722546 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
Neuromyelitis Optica Spectrum Disorder, NMOSD
Hoffmann-La Roche · started 2026-05-06
📍 Colorado
NCT05199688 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Phase 1b/2 Study of IV Sarilumab in Adult With RA
Rheumatoid Arthritis
Sanofi · started 2026-07-02
📍 Florida · Pennsylvania · Texas
NCT07704580 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Psoriatic Arthritis
Takeda · started 2025-03-03
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Louisiana · Maryland
NCT06671483 on ClinicalTrials.gov ↗
By invitation Phase 1
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Neoplasms
USWM CT, LLC · started 2018-04-09
📍 Georgia · Maryland · Michigan · Missouri · New York · North Carolina · Oregon · Pennsylvania
NCT03391778 on ClinicalTrials.gov ↗
Active Phase 3
A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event
Cardiovascular Disease
AstraZeneca · started 2025-05-28
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Illinois · Indiana
NCT07000123 on ClinicalTrials.gov ↗
Recruiting Phase 3
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Amyotrophic Lateral Sclerosis
Prilenia · started 2026-02-01
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas · Maryland
NCT07322003 on ClinicalTrials.gov ↗
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Priya Life Science (2026). Clinical Trials in the USA Tracker. Available at: https://priyalifescience.com/clinical-trials-usa (Accessed: 13 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one US site, most recently updated first, refreshed daily. This is a curated slice of the full registry, not every US trial. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish and EU sites, see our Ireland and EU trackers.