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Updated 11 Aug 2026 · ClinicalTrials.gov

Clinical Trials in Newcastle upon Tyne

← All UK trials

The most recently updated industry-sponsored clinical trials recruiting across the United Kingdom — searchable by condition, sponsor, phase and city. Refreshed daily from the ClinicalTrials.gov registry.

17
Recruiting now
19
Studies tracked
Newcastle upon Tyne
Selected city
Recruiting Phase 2
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca · started 2025-06-27
📍 Bradford · Cottingham · Glasgow · Harrow · London
NCT07082738 on ClinicalTrials.gov ↗
Active Phase 2
Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Vertex Pharmaceuticals Incorporated · started 2025-11-19
📍 Birmingham · London · Newcastle upon Tyne · Sheffield
NCT07161037 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)
Regeneron Pharmaceuticals · started 2024-10-30
📍 Liverpool · York · Bristol · London · Newcastle upon Tyne
NCT06541704 on ClinicalTrials.gov ↗
Recruiting Phase 3
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Primary Biliary Cholangitis
Gilead Sciences · started 2023-09-07
📍 Hull · Ipswich · Leeds · London · Newcastle upon Tyne
NCT06051617 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping
Duchenne Muscular Dystrophy (DMD)
Dyne Therapeutics · started 2022-08-12
📍 Liverpool · Newcastle upon Tyne · Leeds · Bristol · London
NCT05524883 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor
PMV Pharmaceuticals, Inc · started 2020-10-29
📍 London · Newcastle upon Tyne
NCT04585750 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Adenovirus Infections
SymBio Pharmaceuticals · started 2026-03-17
📍 Birmingham · Leeds · London · Manchester · Newcastle upon Tyne
NCT07387367 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
Dravet Syndrome
Longboard Pharmaceuticals · started 2024-09-25
📍 Newcastle upon Tyne · Glasgow · London
NCT06660394 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
BeOne Medicines · started 2025-06-11
📍 Bournemouth · Headington · Leeds · London · Metropolitan Borough of Wirral
NCT06943872 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy
Advanced Solid Tumors
AstraZeneca · started 2025-11-25
📍 Newcastle upon Tyne · Sutton
NCT07161414 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Heart Failure, Left Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC · started 2023-05-31
📍 London · Newcastle upon Tyne
NCT05714085 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
Hemophilia A, Hemophilia B
Pfizer · started 2022-12-09
📍 Newcastle upon Tyne · Birmingham · London · Manchester
NCT05611801 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC · started 2021-05-12
📍 Cambridge · Glasgow · London · Newcastle upon Tyne · Sheffield
NCT07218029 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Non-small Cell Lung Cancer (NSCLC)
Bristol-Myers Squibb · started 2026-03-16
📍 Manchester · Newcastle upon Tyne · Birmingham · Cambridge · Cardiff
NCT07361497 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Obesity, Weight Gain
Eli Lilly and Company · started 2024-06-03
📍 Cambridge · Glagow · Leeds · Leicester · Liverpool
NCT06439277 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Chronic Kidney Disease
Boehringer Ingelheim · started 2025-12-09
📍 Birmingham · Bristol · Glasgow · Liverpool · London
NCT07107945 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Systemic Lupus Erythematosus, Active Refractory Rheumatoid Arthritis
Amgen · started 2025-07-16
📍 Cambridge · Edinburgh · Leicester · Newcastle upon Tyne
NCT06570798 on ClinicalTrials.gov ↗
Recruiting Phase 3
Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN
C3 Glomerulopathy, Immune-complex-membranoproliferative Glomerulonephritis
Novartis Pharmaceuticals · started 2019-10-03
📍 Newcastle upon Tyne · Cardiff · London
NCT03955445 on ClinicalTrials.gov ↗
Recruiting Phase 3
Pridopidine Phase 3 Study in Huntington's Disease
Huntington Disease
Prilenia · started 2026-07-01
📍 Aberdeen · Birmingham · Cardiff · Liverpool · Newcastle upon Tyne
NCT07609108 on ClinicalTrials.gov ↗
No trials match your search.

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London · 117 Manchester · 36 Birmingham · 34 Glasgow · 30 Leeds · 29 Cambridge · 25 Oxford · 23 Bristol · 20 Newcastle upon Tyne · 19 Sheffield · 17 Leicester · 16 Liverpool · 15 Cardiff · 14 Southampton · 14 Sutton · 14 Edinburgh · 12

Browse by condition

Chronic Lymphocytic Leukemia · 5 Obesity · 4 Huntington Disease · 3 Advanced Solid Tumor · 3 Neoplasms · 3 Breast Cancer · 3 CLL · 3 Cancer · 2 Recurrent Pericarditis · 2 Pericarditis · 2 Metastatic Cancer · 2 Crohn's Disease · 2 Niemann-Pick Type C Disease · 2 Non-small Cell Lung Cancer (NSCLC) · 2 Multiple Sclerosis · 2 Idiopathic Pulmonary Fibrosis · 2
Cite this page

Priya Life Science (2026). Clinical Trials in the UK Tracker. Available at: https://priyalifescience.com/clinical-trials-uk/city/newcastle-upon-tyne (Accessed: 12 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one UK site, most recently updated first, refreshed daily. This is a curated slice of the registry, not every UK trial; UK studies may also be registered on ISRCTN. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our UK Pharma Salary Guide, or see our Ireland, EU and USA trackers.